Sleep duration: A review of genome-wide association studies (GWAS) in adults from 2007 to 2020

A modest body of research exists in the area human sleep genetics, which suggests that specific phenotypes are, like many other complex traits, somewhat heritable. Until 2007 into genetics relied solely on twin studies, but last 13 years with advent huge biobanks and very large-scale genome-wide association field molecular has seen important advances. To date, majority have focused self-reported duration, recent studies objectively-measured emerged. These genetic discovered multiple common variants as such, provided insight potential biological pathways, causal relationships between duration disease outcomes using Mendelian randomisation. They also shown heritability these traits may not be high previously estimated. This article is first to provide a detailed review advances epidemiology duration. Studies were identified both GWAS Catalog PubMed for completeness. Focus published including whether how they elucidated biology advanced knowledge health.